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帕罗西汀治疗脑外伤后情感障碍30例

Analysis of 30 cases of emotional disturbance after brain trauma receiving paroxetine treatment

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【作者】 刘志超李承晏曾庆杏毛善平

【Author】 LIU Zhi-chao,LI Cheng-yan,ZENG Qing-xing,MAO Shan-ping ( Department of Neurology,The First Affiliated Hospital of Hubei Medical University,Wuhan 430060, China )[

【机构】 湖北医科大学附属第一医院神经科!武汉430060

【摘要】 目的 :探讨治疗脑外伤后情感障碍的有效方法。方法 :应用帕罗西汀和阿米替林治疗脑外伤情感障碍患者各 30例 ,治疗组用帕罗西汀 2 0mg/d ,对照组用阿米替林 75mg/d ,均治疗 8周。观察其疗效、不良反应及复发率。结果 :帕罗西汀较阿米替林能显著地改善脑外伤后情感障碍患者的症状 ,且不良反应轻 ,复发率低。结论 :帕罗西汀是治疗脑外伤后情感障碍的有效药物。

【Abstract】 Objective:To search for effective therapy for emotional disturbance after brain trauma.Methods:The study was conducted in 60 patients with emotional disturbance after brain trauma.They were equally divided to receive paroxetine 20mg daily or amitriptyline 75mg daily for 8 weeks and their efficacy,side effects and recurrence were observed.Results:The emotional disturbance after brain trauma was significantly improved after paroxetine treatment in comparison with amitriptyline with a lower incidence of side effect and recurrence.Conclusion:Paroxetine is an effective agent for treatment of emotional disturbance after brain trauma. [

  • 【文献出处】 中国新药杂志 ,Chinese New Drugs Journal , 编辑部邮箱 ,2000年11期
  • 【被引频次】1
  • 【下载频次】20
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