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补阳还五汤合用维生素E对急性脑梗死患者自由基及血液流变性的影响
Influences of Buyang Huanwu Decoction (补阳还五汤) combined with Vitamine E on free radicals and hemorrheology in patients with acute cerebral infarction
【摘要】 目的:观察补阳还五汤合用维生素E治疗急性脑梗死的疗效及对患者血中自由基和血液流变性的影响。方法:将56 例患者随机分为治疗组(34 例)和对照组(22 例),2 组患者常规治疗相同,治疗组加用口服补阳还五汤,每日1剂,维生素E100 m g,每日1 次。2 组均于治疗14 日后观察血中自由基及血液流变学指标变化。结果:治疗组总有效率88.2% ,对照组总有效率59.1% ,治疗组疗效显著优于对照组(P< 0.05);治疗组治疗后血中自由基和血液流变学指标与治疗前及对照组治疗后比较均有显著改善(P< 0.01 或P< 0.05)。结论:补阳还五汤合用维生素E治疗急性脑梗死可清除血中自由基,增强抗自由基物质的活力,改善血液流变性,降低血粘度。
【Abstract】 Objective:To observe the curative effects of Buyang Huanwu Decoction(BYHWD,补阳还五汤) combined with Vitamine E on acutely cerebral infarction(ACI) and its influences on blood free radicals and hemorrheology of patients.Methods:56 patients were randomly divided into treated group ( n =34) and control group ( n =22).The conventional therapy was same to both groups otherwise in treated group the BYHWD taken orally once a day and Vitamine E 100 mg once a day were added.After 14 day therapy the changes in the parameters of blood free radicals and rheology were observed.Results:The total effective rate in treated group was 88 2% but it was 59 1% in control group so that the curative effects in treated group were significantly superior to those in control group ( P <0 05).After therapy in treated group the parameters of blood free radicals and rheology in comparison with before therapy and control group after therapy had significant differences ( P <0 01 and P <0 05).Conclusions:BYHWD combined with Vitamine E is able to eliminate the blood free radicals to promote the activities of antifree radical substances,to improve the hemorrheology,and to decrease the blood viscosity.Its curative effects in treatment for ACI are marked.
【Key words】 acute cerebral infarction; Buyang Huanwu Decoction; Vitamine E; free radicals; hemorrheology;
- 【文献出处】 中国中西医结合急救杂志 ,INTEGRATED TRADITIONAL CHINESE AND WESTERN MEDICINE IN PRACTICE OF CRITICAL CARE MEDICINE , 编辑部邮箱 ,2000年01期
- 【分类号】R743.3
- 【被引频次】13
- 【下载频次】91