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高血压病的胰岛素抵抗、脂质及红细胞膜ATP酶活性变化规律

THE CHANGES OF INSULIN RESISTANCE, LIPID AND ACTIVITY OF ATPASE IN PATIENTS WITH ESSENTIAL HYPERTENSION

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【作者】 贺燕勤于顾然范德荣郭云庚

【Author】 He Yanqing, Yu Guran, Fan Derong, Guo Yungen The Second Affiliated Hospital of Nanjing Chinese Medicine University, Nanjing 210017

【机构】 南京中医药大学第二附属医院!210017南京中医药大学第一附属医院!210029福建省人民医院!350004

【摘要】 对 92例高血压病人的研究发现 :高血压病人的胰岛素抵抗等在高血压不同分期 ,肥胖与否等方面存在明显差异。且其抵抗程度与严重程度有关。

【Abstract】 Objective: To investigate the changes of IR, activity of ATPase, lipid in patients with EH. Methods: 92 patients with EH were observed, among them 56 cases were obese, 36 cases were nonobese. On the other hand, of the 92 patients, 21 had EH I, 30 had EH II, 41 had EH III. 31 healthy people were taken as the control group. Results: The reverse of fasting plasma glucose and insulin product was used as insulin sensitivity index. The activity of ATPase in the erythrocyte membrane was measured with Vincenzi’s assays. The serum lipoprotein (2) concentration was measured with enzyme-linked imuosorbent assays (ELISA) Con clusions: IR or HIS in closely associated with the pathogenesis of EH and OEH is more serve than NOEH.

  • 【文献出处】 中国现代医学杂志 ,CHINA JOURNAL OF MODERN MEDICINE , 编辑部邮箱 ,2000年08期
  • 【分类号】R544.1
  • 【被引频次】10
  • 【下载频次】26
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