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脉络膜黑色素瘤的X-刀治疗

The X-knife treatment for choroidal melanoma

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【作者】 刘原照肖素华高鸿刘明远

【Author】 LIU Yuanzhao, XIAO Suhua, GAO Hong, et al. (Department of radiotherapy, Beijing Hospital, Beijing 100730)

【机构】 北京医院放疗科! (北京010000)010000)

【摘要】 目的 探讨X-刀治疗脉络膜黑色素瘤的疗效及照射剂量。 方法 采用60%~80%等剂量曲线覆盖靶区,肿瘤边界最小剂量18.4~27Gy,平均37.9Gy。治疗脉络膜黑色素瘤9例。 结果 平均随访18.7个月。眼球保留率88.9%(89)。治疗后1年计算机体层摄影(CT)、磁共振成像(MRI)检查结果示:肿瘤消失1例,缩小4例,无变化3例,进展1例。肿瘤周边剂量≤20Gy组有效率为25%(14)比>20Gy组的80%(45)低,但由于例数少而无统计学差异。 结论 X-刀是治疗脉络膜黑色素瘤一种有效的方法。

【Abstract】 Objective To evaluate the effect of the X-knife on choroidal melanoma and dose of radiosurgery. Method 9 patients with choroidal melanoma were treated by X-knife. The edge isodose line range from 60% to 80%. The mean minimum dose was 21.9Gy(range 18.4-27Gy) and the maximum dose was 37.9Gy (27.5-58Gy). Result Median follow-up was 18.7 months. The rate of eye ball preservation was 88%. Follow-up imaging findings showed disappearance in 1 patient, decrease in size of tumour in 4 patients, no change in 3 patients and increase in 1 patient. The effective rate of the adge dose≤20Gy and >20Gy groups were 25% (14) and 80%(45), respectively. Conclusion The X-knife is effective method for choroidal melanoma.

【关键词】 脉络膜黑色素瘤X-刀
【Key words】 choroidal melanomastereotactic rediosurgery
  • 【文献出处】 中国微侵袭神经外科杂志 ,Chinese Journal of Minimally Invasive Neurosargery , 编辑部邮箱 ,2000年03期
  • 【分类号】R730.55
  • 【被引频次】1
  • 【下载频次】25
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