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猪、犬旋毛虫成虫免疫原性试验

THE STUDY ON IMMUNOGENICITY OF ADULT ANTIGENS OF TRICHINELLA FROM SWINE AND DOG

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【作者】 宋铭忻曹荣峰张桂红路义鑫王裕卿

【Author】 SONG Ming xin,CAO Rong feng,ZHANG Gui hong,LU Yi xin,WANG Yu qing [WT5”BX](Northeast Agricultural University,Harbin 150030, China) [WT5”HZ]

【机构】 东北农业大学动物医学院!哈尔滨150030

【摘要】 通过提取猪、犬旋毛虫成虫抗原 ,制备成虫油佐剂免疫原 ,在小鼠体内进行同源特异性免疫试验和交叉免疫试验。试验得到猪旋毛虫成虫抗原同源免疫减虫率为 55.80 % ,其对犬旋毛虫的交叉免疫减虫率是 35.1 1 % ;犬旋毛虫成虫抗原同源免疫的减虫率为 39.0 0 % ,其对猪旋毛虫的交叉免疫减虫率是 2 4 .96%。试验结果揭示 ,猪、犬旋毛虫成虫具有一定的免疫原性 ,其交叉免疫减虫率低于同源特异性免疫。猪旋毛虫成虫抗原对犬旋毛虫的交叉免疫与犬旋毛虫自身的同源特异性免疫差异不显著

【Abstract】 Antigens derived from adult of Trichinella from swine and dog were injected in mice respectively.The mice were challenged with muscle larvae of Trichinella from swine and dog one week later,the muscle larvae reduction was observed on 35 day after infection.The results showed that the reduction of T.swine adult of homo immunity was 55.80%,and that of T.dog was 39.00%;moreover,they both had cross immunity reactions:by T.swine immunity,the reduction of T.dog was 35.11%,conversely,by T.dog immunity,the reduction of T.swine was 24.96%.The results indicated that adult of Trichinella from swine and dog is normal in its immunogenicity,the protection rate of cross immunity is lower than that of homo immunity.

【关键词】 旋毛虫成虫交叉免疫
【Key words】 Trichinella adultcross immunityswinedog
【基金】 黑龙江省“九五”攻关课题! :G96 B3- 4;黑龙江省自然科学基金! C940 0 8
  • 【文献出处】 中国兽医寄生虫病 ,CHINESE JOURNAL OF VETERINARY PARASITOLOGY , 编辑部邮箱 ,2000年04期
  • 【分类号】S855
  • 【被引频次】1
  • 【下载频次】50
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