【摘要】 考察虫类药物对腺嘌呤致慢性肾功能不全大鼠的治疗作用及其机理。采用氢气排除记录大鼠肾血流量 ;用改良的戈氏紫外吸收法测血中中分子物质 (MMS)含量 ;检测血红蛋白 Hb及红细胞膜 Na+ K+ ATP酶活性 ;镜下观察大鼠肾组织病变的情况。结果 :用药后大鼠肾血流量明显增加 ,MMS降低 ,Hb和红细胞膜Na+ K+ ATP酶活性增加 ,肾组织病变明显改善。更多还原

【Abstract】 The effects and mechanism of drug prepared from insects were studied in rat model of chronic renal failure (CRF) induced by adenine.The results showed that drug prepared from insects (5,12 5g/kg for 15 days) could obviously increase the renal blood flow and Hb,decrease medial molecular substance(MMS),enhance the activity of Na +K +ATPase and improve the pathological changes of renal tissue.更多还原