【摘要】 目的　评价检测患者血清特异ＩｇＧ４ 指导临床应用的价值。方法　检测血清特异ＩｇＧ４ 并与患者脑组织内囊尾蚴感染程度、临床表现、杀虫反应等进行比较分析。结果　血清特异ＩｇＧ４ 水平与患者有无绦虫史无明显关系。脑型合并皮下结节患者血清特异ＩｇＧ４ 阳性率和阳性强度明显高于单纯型脑囊虫病，而单纯型脑囊虫病患者与皮下结节消失的脑囊虫病患者之间血清特异ＩｇＧ４ 水平无明显差异。患者脑组织内囊尾蚴感染程度和抗囊疗程以及服药后的杀虫反应等均与血清特异ＩｇＧ４ 水平存在明显相关关系。结论　检测血清特异ＩｇＧ４ 对脑囊虫病患者疾病状态评价和抗囊药物的应用均具有重要意义。更多还原

【Abstract】 Aim To assess the clinical application evaluation of testing the specific IgG4 in sera of cerebral cysticercosis patients Method The specific IgG4 in sera was tested and compared with infectiosity of cysticercus in patient’s brain tissue,clinical manifestation,side reaction of anti-cysticercus and so on Results No significant relationship was found between the level of specific IgG4 in sera of these cases and history of taeniasis However,the positive rate and intensity of specific IgG4 in sera of cerebral cysticercosis patients with subcutaneous nodules was found to be significantly higher than those in sera with simple cerebral cysticercosis patients There’re no differences of specific IgG4 levels between the simple cerebral cysticercosis patients and cases with subcutaneous nodules disappeared before collection of sera The patient’s infectiosity of cysticercus and different courses of treatment or aside reaction of anti-cysticercus therapy all significant relationship with the level of specific IgG4 in sera Conclusion This method can be used to assess the disease status and instruct clinic application of anti-cysticercus therapy更多还原