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发现2个FGFR1细胞外段同源的cDNA片段

Discovery of two FGFR1 extracellular domain homologous-cDNA fragments

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【作者】 郭京丽吴秀丽王丽颖杨贵贞

【Author】 GUO Jing Li,WU Xiu Li,WANG Li Ying et al The School of Basic Medical Sciences,Norman Bethune University of Medical Sciences,Changchun 130021

【机构】 白求恩医科大学基础医学院!长春130021

【摘要】 目的 :克隆表达人成纤维细胞生长因子受体。方法 :采用RT PCR法。结果 :在钓取人cDNA的过程中 ,意外地钓取到 2个与FGFR1细胞外段同源的cDNA片段 ,经克隆和DNA序列分析发现它们是FGFR1细胞外源的cDNA片段。结论 :虽然对这 2个cDNA片段的功能尚不明确 ,但这种抓住新现象并进行探究的意识对科研很重要

【Abstract】 Objective:To clone and express fibroblast growth factor receptor1 Methods:RT PCR is used to isolate FGFR1 cDNA Results:In the process of isolating the extracellular domain cDNA of fibroblast growth factor receptor 1 (FGFR1) from human lung fibroblasts, discovered two cDNA species After analysis of the cDNAs by cloning and sequencing,have indentified that the two species are FGFR1 extracellular domain homologous cDNA Conclusion:Don’t know the function of the two cDNA but it is very important that a net phenomenon in the research should be taken and studied Here only present the discovery of the isoforms whose functions will be studied in the future

【关键词】 意外FGFR1cDNA克隆
【Key words】 Unexpected FGFR1 cDNA Cloning
  • 【文献出处】 中国免疫学杂志 ,CHINESE JOURNAL OF IMMUNOLOGY , 编辑部邮箱 ,2000年09期
  • 【分类号】R392
  • 【下载频次】38
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