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荟萃分析评价呼吸系统感染促发缺血性脑中风的危险性

The Evaluation on the Risk of the Ischemic Stroke Triggered by Respiratory Infection with Meta analysis

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【作者】 李国庆阎文双张捧玉周群拉苗秀荣张艳红

【Author】 Li Guoqing,et al;Hebei Medical College for Continuing Education,Baoding 071000

【机构】 河北省职工医学院!保定071000邢台市第三医院黑河市第一人民医院

【摘要】 目的:评价呼吸系统感染诱发缺血性脑中风的危险性。方法:荟萃分析。结果:对6个近期感染与缺血性脑中风(IS)发作关系的病例对照研究,对象按呼吸系统感染和非呼吸系统感染分两个层次分别进行荟萃分析,6个研究累积IS病例719例,有感染史者171例(23.78%),其中呼吸系统感染119例(16.55%),非呼吸系统感染52例(7.23%)。累积对照775例,有感染史者60例(7.74%),其中呼吸系统感染36例(4.65%),非呼吸系统感染24例(3.10%)。经齐性检验,两个层次结果一致性均很好。经加权和合并,呼吸系统感染合并OR值4.30(2.91~6.36),非呼吸系统感染OR值2.57(1.46~4.48)。结论:呼吸系统感染是促发IS发作的最重要的感染性疾病。

【Abstract】 Objective:To evaluate the risk of the ischemic stroke triggered by respiratory infection.Methods:Meta analysis.Results:Subjects in 6 case control studies on the relationship between recent infection and ischemic stroke(IS) were separated into two strata:respiratory infection and non respiratory infection,and then analyzed by meta analysis.The cumulative cases were 719,among them,the patients with recent infection were 171(23 78%),of whom respiratory infection cases were 119(16 55%),other infection cases were 52(7 23%).The accumulative controls were 775,among which,the controls with recent infection were 60(7 74%),of whom respiratory infection cases were 36(4 65%),other infection cases were 24(3 1%).These 2 strata were homogenous respectively by means of homogeneity test.The pooled OR value of respiratory infection was 4 30(95% CI 2 91~6 36) and other infection was 2 57(95% CI 1 46~4 48) after being weighed and pooled.Conclusion:Respiratory infection was the most important infectious disease for ischemic stroke ictus.

  • 【文献出处】 中国慢性病预防与控制 ,CHINESE JOURNAL OF PREVENTION AND CONTROL OF CHRONIC NON-COMMUNICABLE DISEASES , 编辑部邮箱 ,2000年01期
  • 【分类号】R743.3
  • 【被引频次】28
  • 【下载频次】94
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