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兴安杜鹃挥发油抗气道变应性炎症的研究

Inhibition effects of volatile oil of dauricum on allergic inflammation of mice airway

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【作者】 杨宗辉侯刚张红军尹建元

【Author】 Yang Zonghui,Zhang Hongjun,Hou Gang et al (Department of pharmaceutics,the 3rd Clinical Medical,Norman Bethune University of Medical Sciences,Changchon 130031)

【机构】 白求恩医科大学第三临床医院药剂科!长春130031长春市朝阳区卫生局白求恩医科大学有机化学教研室

【摘要】 目的 探讨兴安杜鹃挥发油对小鼠气道变应性炎症的治疗。方法对昆明种小鼠采用超声雾化吸入1%卵清蛋白生理盐 水致敏,建立小鼠气道变应性炎症模型,检测并比较各组间肺组胺浓度及肺组织病理学变化。结果治疗组较模型组肺组胺浓度差异显 著(P<0.05),肺组织病理学变化表明,治疗组较模型组有明显恢复,与正常对照组接近。结论兴安杜鹃挥发油具有明显的抗炎、平喘作用。

【Abstract】 Objective To study the inhibition effects of volatile oil of dauricum(VOD) on allergic inflammation of mice airway. Methods Ovalbunmin inhalation in sensitized mice producing the ariway hyperresponsive animal model,These animals randomly divided into three groups:the normal control,the treated and the model control,with 15 mice per group. Examining the lung histamine and observing lung pathologic changes. Results The histamine in lung of the treated group was significantly decreased comparing with the model control group(P<0. 05),with significant protetion after the therapy. Conclusions VOD has suppressive effects on asthmatic inflammation of the airway.

  • 【文献出处】 中国老年学杂志 ,Chinese Journal of Gerontology , 编辑部邮箱 ,2000年03期
  • 【被引频次】1
  • 【下载频次】132
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