【摘要】 目的 :探讨血清转化生长因子 β1 (TGF β1 )肾细胞癌侵袭性的作用。方法 :应用酶联免疫吸附试验 (ELISA)方法检测 17例正常人血清TGF β1 和 17例肾细胞癌病人根治术前后TGF β1 浓度。结果 :所有肾细胞癌根治术前病人血清TGF β1 浓度明显高于正常对照组 (P <0 .0 1) ,根治术后血清TGF β1 浓度明显下降 (P <0 .0 1)。结论 :血清TGF β1 浓度可能成为一种判断肾细胞癌预后的瘤标更多还原

【Abstract】 Objective:To detect the role of transforming growth factor β 1(TGF β 1)on aggressiveness of renal carcinoma cell.Methods:Serum TGF β 1 was measured by means of enzymelinked immunsorbent assay(ELISA) in 17 cases of renal cell carcinoma(RCC) before and after radical nephrectomy.17 cases of normal subjects were employed as healthy controls.Results:In all case of RCC the levels of TGF β 1 were significant higher than those of the healthy controls( P <0.01).After the operation,serum TGF β 1 was dramatically decreased(P<0.01).Conclusions:Serum TGF β 1 is a possible tumorprognostic marker in RCC.更多还原