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ELISA检测妇科肿瘤患者伴发弓形虫感染的调查

DETECTION OF TOXOPLASMA INFECTION IN WOMEN WITH GYNAECOLOGIC NEOPLASMS USING ELISA 

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【作者】 黄鹤阎福华李川江赵美毅汤俊文李向荣

【Author】 HUANG He 1, YAN Fu hua 2, LI Chuan jiang 1,ZHAO Mei yi 2, TANG Jun wen 2, LI Xiang rong 2 (1 Institute of Virology, Hubei Academy of Medical Sciences, Wuhan 430079 2 Department of Gynaecology, Hubei Cancer Hospital, Wuhan 430079)

【机构】 湖北省医学科学院病毒研究所!武汉430079湖北省肿瘤医院妇科!武汉430079

【摘要】 [目的 ]了解妇科宫颈癌患者伴发弓形虫感染的情况。[方法 ]采用 EL ISA法检测弓形虫 Ig G、Ig M抗体和循环抗原。 [结果 ]宫颈癌、妇科良性肿瘤、其它疾患妇女 3组人群的弓形虫感染率分别为 :44 .0 % (2 2 / 5 0 )、2 5 .4% (15 / 5 9)和 2 0 .3% (2 8/ 138)。 3组人群 Ig G阳性率分别为 2 0 .0 0 %、11.86 %和 10 .87% ,Ig M阳性率分别为2 0 .0 0 %、13.5 6 %和 8.70 % ,循环抗原阳性率分别为 14.0 0 %、5 .0 9%和 1.45 %。 [结论 ]宫颈癌患者弓形虫感染率明显高于其它两组人群 ,以循环抗原和 Ig M阳性尤为明显

【Abstract】 Objective] To understand the concurrent in Toxoplasma infection among women with cervical cancer. [Methods] The anti Toxoplasma IgG, IgM antibodies (Abs) and circulating antigens (CAg) in 247 sera ( from 50 cases with cervical cancer in group 1, 59 cases with gynaecological benign tumors in group 2 and 138 cases with other diseases in group 3 ) were detected by ELISA. [Results] The total positive rates of the CAg and the Abs in the three groups were 44 0% (22/50), 25 4% (15/59) and 20 3% (28/138), respectively. The positive rates were 20 0%, 11 9% and 10 9%, respectively for IgG 20 0%, 13 6% and 8 7%, respectively fot IgM and 14 0%, 5 1% and 1 4% respectively for CAg. [Conclusion] The Toxoplasma infection rate of the cervical cancer group was higher than those of the other two groups, particularly the positive rates of CAg and IgM.

【关键词】 弓形虫感染宫颈肿瘤ELISA循环抗原IgMIgG
【Key words】 Toxoplasma infectioncervical neoplasmsELISAcirculating antigenIgMIgG.
  • 【文献出处】 中国寄生虫学与寄生虫病杂志 ,CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES , 编辑部邮箱 ,2000年03期
  • 【分类号】R446.61
  • 【被引频次】15
  • 【下载频次】51
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