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组织细胞移植用生物微胶囊技术介绍
Biomicrocapsule membrane for cell and tissue transplantation
【摘要】 提供一种组织细胞移植治疗的免疫隔离方法。方法 使海藻酸钠/聚赖氨酸(APA)生物微胶囊具生物相容性、适宜强度与通透性,包埋组织细胞。结果 包埋相应移植组织细胞,取得了治疗糖尿病等疾病模型的成功。结论 生物微胶囊作为组织细胞移植的免疫隔离工具治疗神经内分泌或基因缺损性疾病具安全性与可行性。
【Abstract】 Objective To Provide a simple and safe way in protecting living cells from immune rejection for transplantation therapies. Methods Enclose cells in Alginate-poly-l-lysine (APA) biomicrocapsules which have to be satisfied the following requirements: ① biocompatibility, ② strength, ③permeability. Results The transplantated cells survived and had prominence therapy function in experimental animals. Conclusions Biomicrocapsules are feasible tools for cells immun-transplantation.
- 【文献出处】 中华整形外科杂志 ,Chinese Journal of Plastic Surgery and Burns , 编辑部邮箱 ,2000年05期
- 【分类号】R617
- 【被引频次】40
- 【下载频次】181