【摘要】 为了防治烧伤患者由耐甲氧西林葡萄球菌引起的医院感染。方法　对 1997年 6月～ 1998年 6月我院烧伤科医院感染患者的创面分泌物、尿、痰、大便、血做细菌培养和体外药物敏感试验。结果　从烧伤患者分离的金黄色葡萄球菌和凝固酶阴性的葡萄球菌 (CNS)对甲氧西林的耐药率分别为 89.4%和 6 0 % ;不同标本葡萄球菌的检出率由高到低依次为创面分泌物、尿、痰、大便、血液。结论　葡萄球菌可引起烧伤患者的创面、尿路、呼吸道、消化道、血液的感染 ;感染的菌株以耐甲氧西林金黄色葡萄球菌 (MRSA)和耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)为主 ,而且大多数菌株呈多重耐药 ;创面的大小与烧伤的深度、第三代头孢和氟喹诺酮类抗生素的不合理应用以及住院时间 ,是引起烧伤患者葡萄球菌医院感染的危险因素 ;控制这些因素可以减少此类感染的发生。更多还原

【Abstract】 OBJECTIVE To control the nosocomial infection caused by meticillin-resistant Staphylococcus in burn patients. METHODS The specimens of burn wound excreta, urine, stool and blood of burn patients were collected to isolate pathogenic organisms and the susceptibility tests for antibacterial agents were performed by Kirby-Bauer method. RESULTS The rates of meticillin-resistant Staphylococcus(MRSA) and meticillin-resistant coagulase-negative Staphylococcus(MRCNS) were 89.4% and 60%. CONCLUSIONS Staphylococcus may cause infections in burn wound, urinary tract, respiratory tract, the alimentary canal and blood. Most of them are MRSA and MRCNS and multidrug resistant. Severe burn, abuse of third-generation cephalosporins and fluoroquinolones and long hospital stay may be the risk factors for staphyiococcal nosocomial infections.更多还原