【摘要】 目的　探索O15 7大肠杆菌在福建省人兽及食物中的存在情况 ,并了解这些检出菌的生物学特性。方法　 1997～ 1998年选莆田、福州等地检查腹泻患者粪便、畜禽粪便标本及肉类标本2 72 5份 ,以血清学方法检测O15 7大肠杆菌。结果　先后从猪、鸽、牛、鸡、鸭等动物及腹泻患者中检出 76株O15 7大肠杆菌。据血清学及动力试验结果分类 ,33株O15 7∶H7,2 1株O15 7∶NM ,2 2株O15 7∶H ?,其中以猪检出率最高。检出菌株可致人腹泻 ,小鼠肠道明显病变 ,但并不产生Vero细胞毒素 ,也不产生耐热肠毒素与不耐热肠毒素。结论　福建地区存在 3种类型O15 7大肠杆菌 ,但O15 7∶H7与O15 7∶NM在致病因子上与国际报道有异 ,可能存在新的致病因子更多还原

【Abstract】 Objectives To understand the distribution of Escherichia coli O157 ( E. coli O157) in human beings, livestock and fowls in Fujian Province, and biological features of the isolated strains. Methods Fecal specimens from diarrheal patients, livestock and fowls and meat specimens in Putian and Fuzhou were collected for detection of E coli O157 during 1997 1998 Results A total of 2 725 specimens were detected, and 76 strains of E coli O157 were isolated from pigs, pigeons, cattle, chickens,ducks,et al., as well as from the diarrheal patients. These strains could be classified into three types according to their serological tests, including 33 strains of O157: H7,21 strains of O157:NM,and 22 strains of O157:H? Detecting rate of E coli O157 from pigs was the highest The isolated strains could cause diarrhea in human and obvious pathological changes in the intestines of mice, but could not produce cytotoxin Vero, or heat stable or heat liable enterotoxin LT or ST. Conclusions There were three types of E coli O157 in Fujian But, pathogenic factors of O157: H7 and O157: NM were different from those reported abroad It suggested that there possibly existed some new pathogenic factors.更多还原