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颅内原发性黑色素瘤的诊断及治疗

Primary melanoma of the central nervous system

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【作者】 张义陈立群吴劲松秦智勇张福林

【Author】 ZHANG Yi , CHEN Liqun, WU Jinsong, Department of Neurosurgery, Huashan Hospital, Shanghai Medical University, Shanghai 200040, China.

【机构】 上海医科大学华山医院神经外科江西上饶地区人民医院神经外科

【摘要】 目的 探讨颅内原发性黑色素瘤的诊治方法。 方法 分析 196 8年以来收治的 6例颅内原发性黑色素瘤的临床表现、诊治方法和疗效。 结果 临床表现无特异性 ,CT及MRI均难以明确诊断。肿瘤全切除 1例 ,大部切除 3例 ,部分切除 1例 ,活检 1例。诊断颅内原发性恶性黑色素瘤 3例 ,脑膜黑色素瘤 3例。随访 5例 ,3例恶性黑色素瘤患者死亡 ,2例脑膜黑色素瘤 1例长期卧床 ,1例恢复正常生活。 结论 颅内原发性黑色素瘤发病率低 ,误诊率高 ,治疗以手术切除为主 ,预后与肿瘤的良恶性及肿瘤的部位有关 ,在保证生存质量的前提下全切除肿瘤为最佳治疗方案

【Abstract】 s Objective To investigate the status of diagnosis and treatment of primary melanoma of the central nervous system. ]Methods Six patients with primary melanoma of the central nervous system underwent surgery in our department between 1968-1999. Clinical presentation, operative findings, histological diagnosis, and prognosis were reviewed. Results No typical symptom occurred in these patients. The lesions can mimic meningiomas and acoustic neuromas in location and radiological appearance. Total removal of tumors was only achieved in one case. Histological examination showed malignant lesions in 3 cases and benign lesions in others. Five cases were followed up and only two were alive. Conclusions Primary melanomas are extremely rare tumors of the central nervous system. Surgical removal of the lesion may result in prolonged remission or cure.

【关键词】 脑肿瘤黑素瘤
【Key words】 Brain neoplasmsMelanoma
  • 【文献出处】 中华外科杂志 ,Chiese Journal of Surgery , 编辑部邮箱 ,2000年04期
  • 【分类号】R739.41
  • 【被引频次】10
  • 【下载频次】152
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