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急性有机磷中毒中间综合征17例临床分析

Clinical analysis of 17 cases of intermediate syndrome after acute organophosphorus pesticides poisoning

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【作者】 庄武平陈健杨尔隆林星

【Author】 ZHUANG Wuping,CHEN Jian,YANG Erlong,et al.Fuqing Municipal Hospital,Fujian 350300,China

【机构】 福建省福清市医院内科

【摘要】 目的 探讨急性有机磷农药中毒并发中间综合征 (intermediatesyndrome ,IMS)的诊断与治疗。方法 回顾性分析 17例IMS患者的临床表现。结果 有机磷农药中毒并发IMS的患病率为2 .8% ;其呼吸肌麻痹症状出现在急性中毒后 10~ 72h ,9例于 5~ 12min内成功建立人工气道及机械通气 ,其中 7例治愈 ,另 8例因各种原因未及时应用该疗法而死亡。结论 IMS并非罕见 ,临床表现有特殊性 ,应提高认识 ,早期识别 ;建立人工气道与机械通气是抢救的重要方法。

【Abstract】 Objective To investigate the diagnosis and treatment of intermediate syndrome(IMS) after acute organophosphorus pesticides poisoning(AOPP).Methods 17 patients with IMS after AOPP were retrospectively analyzed.Results The occurrence of IMS was 2.8% in total 612 patients with AOPP.The majority of IMS cases were of severe oral AOPP.The respiratory muscle paralysis(RMP) was the most important sign for the diagnosis ,which appeared at 10~72 h after poisoning.9 patients were treated by means of urgent tracheal intubation and mechanical ventilation in 5~12 min,7 of them were cured;The other 8 patients died because of delayed treatment.Conclusion IMS is not a uncommon syndrome.There are some special clinical features such as RMP,which should be identified early.Urgent tracheal intubation and mechanical ventilation are important measures.

  • 【文献出处】 中华劳动卫生职业病杂志 ,CHINESE JOURNAL OF INDUSREIAL HYGIENE AND DCCUPATIONAL DISEASES , 编辑部邮箱 ,2000年02期
  • 【分类号】R595.4
  • 【被引频次】8
  • 【下载频次】30
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