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胆汁及血清中促成核泡相蛋白的检测及临床应用
Determination of biliary vesicular proteins and its clinical significance
【摘要】 目的 检测胆汁及血清中促成核泡相蛋白并进行初步临床研究。方法 应用酶联免疫吸附试验 (Enzyme linkedimmunosorbentassay ,ELISA)检测胆汁及血清中的胆汁泡蛋白含量 ,在胆囊结石患者及对照组中进行比较研究。结果 胆囊胆固醇结石患者胆汁及血清中的 335 0 0胆汁泡蛋白A值分别为 1.717± 0 .376和 1.5 5 6± 0 .710 ,而对照组分别为 0 .2 35± 0 .2 0 5和 0 .5 2 2± 0 .36 2 (P <0 .0 1)。结论 胆囊胆固醇结石患者胆汁及血清中 335 0 0胆汁泡蛋白含量高于非结石患者 ,具有较广阔的临床应用研究价值
【Abstract】 Objective To detect biliary vesicular protein in human bile and serum and evaluate its clinical significance. Method The biliary vesicular protein in bile and serum were detected by ELISA method in patients with gollstone and subjects without gallstone. Results The A value of biliary vesicular protein of gallstone patients in bile and serum were 1.717±0.376 and 1.556±0.710, respectively. But in controls were 0.235± 0.205 and 0.522±0.362 ( P <0.01), respectively. Conclusion With gallstone patients, there is a higher level of bile and serum biliary vesicular protein. It may of help in prediction of gallstone formation and can be used to evaluate the effect of some drugs.
【Key words】 Gallstone; Enzyme linked immunosorbent assay; Biliary vesicular protein;
- 【文献出处】 中华消化杂志 ,CHINESE JOURNAL OF DIGESTION , 编辑部邮箱 ,2000年03期
- 【分类号】R446.1
- 【被引频次】2
- 【下载频次】34