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叶下珠化学成分研究

Studies on Chemical Constituents of Phyllanthus urinaria L

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【作者】 张兰珍郭亚健涂光忠郭五保苗峰

【Author】 ZHANG Lan zhen 1,GUO Ya jian 1,TU Guang zhong 2,GUO Wu bao 3,MIAO Feng 3 1.Beijing University of Traditional Chinese Medicine,Beijing 100029,China; 2.Beijing Institute of Microchemistry,Beijing 100091,China; 3.Shanxi Institute of Traditiona

【机构】 北京中医药大学!北京100029北京微量化学研究所!北京100091陕西中医研究院!陕西西安710003

【摘要】 目的 :研究叶下珠的化学成分。方法 :各种色谱法分离纯化 ,理化和现代波谱法鉴定结构。结果和结论 :分离得到 14个化合物 ,其中 7个分别鉴定为鞣云实精 (Ⅰ ) ,芦丁 (Ⅱ ) ,短叶苏木酚酸 (Ⅵ ) ,isostrictiniin(Ⅸ ) ,老鹳草素 (Ⅹ ) ,没食子酸 (Ⅺ ) ,鞣花酸 (Ⅻ ) ;其中化合物Ⅵ为首次从该植物中得到 ,Ⅸ为首次从该属植物中得到。

【Abstract】 Objective:To investigate the chemical constituents of Phyllanthus urinaria.Method:Various chromatographic techniques were employed for isolation and purification of the constituents. The structures were elucidated by chemical and spectral analyses.Result and Conclusion:Fourteen compounds were isolated and seven of them were identified as corilagin(Ⅰ),rutin(Ⅱ),brevifolincarboxylic acid(Ⅵ),isostrictiniin(Ⅸ),geraniin(Ⅹ),gallic acid(Ⅺ) and ellagic acid (Ⅻ).Compound Ⅵ was found from P. urinaria for the first time and compound Ⅸ was found from genus Phyllanthus for the first time. [

【关键词】 叶下珠多酚鞣花丹宁
【Key words】 Phyllanthus urinariapolyphenolic compoundellagic tannin
【基金】 国家重点科技攻关项目新药研究与产业化开发!( 96 90 1 0 5 172 )
  • 【文献出处】 中国中药杂志 ,CHINA JOURNAL OF CHINESE MATERIA MEDICA , 编辑部邮箱 ,2000年10期
  • 【分类号】R284.1
  • 【被引频次】28
  • 【下载频次】567
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