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THP-Lp乳化剂为主介入化疗栓塞治疗肝癌的临床研究

Clinical Study of Intervening Chemoemobolization with THP-Lp Emulsifier in Treating Liver Neoplasms

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【作者】 王庆良李彩霞孟红

【Author】 Wang Qingliang Li Caixia Meng Hong Department of Radiology Hospital of Shandong Medical University Jinan

【机构】 山东医科大学附属医院放射科导管室!济南市250012

【摘要】 目的:评价以THP-Lp乳化剂进行栓塞的联合化疗治疗肝癌的临床价值。方法:对119例肝癌患者进行了520例次栓塞化疗治疗,其中单纯碘油(Lp)栓塞214例次,碘油与明胶海绵(GF)联合栓塞109例次,经化疗泵栓塞化疗171例次,经动脉栓塞与经皮肝穿刺联合化疗栓塞26例次。结果:本组患者总有效率(CR+PR)为74.8%,肝肿瘤缩小50%以上者占50%。4种治疗的有效率有显著差异(χ2检验P< 0.05),而肿瘤大小改变无明显差异(P >0.05)。结论:以THP-Lp乳化剂为主的联合化疗栓塞应作为肝癌治疗的首选方法,对于乏血型肝癌应采取多种方法联合治疗。

【Abstract】 Objective To evaluate the value of chemoembolization with THP-Lp emulsifier in treating liver neoplasms. Methods One hundred and nineteen patients were treated 520 person-times of chemoembolization including 1 Only chemoembolizing was 214 person-times 2 chemoembolizing with GF embolization 109 person-times 3 chemoembolizing and/or GF embolization with percutaneous treatment 26 person-times and 4 Through dump 171 person-times. Results The overall response rate CR+PR was 74.8% while patients with tumor half shrinkaged accounted for 50%. There existed significant difference χ2 test P< 0.05 among the four methods in total response but there was no significant difference P >0.05 among them in tumor shrinkage. Conclusion Chemoembolization with THP-Lp emulsifier in treating liver neoplasms should be the first choice. As to those tumors lacking of blood supply two or more methods combined each other might get an ideal effectiveness.

  • 【文献出处】 中国肿瘤临床 ,Chinese Journal of Clinical Oncology , 编辑部邮箱 ,2000年12期
  • 【分类号】R735.7
  • 【被引频次】1
  • 【下载频次】32
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