【摘要】 目的：优选香砂六君颗粒制备工艺条件。方法：采用正交设计试验法，以挥发油收率、人参皂苷Ｒｅ收率以及合格颗粒收率为指标，优选油提、水提以及沸腾制粒工艺条件。结果：陈皮、白术、砂仁和木香提油的工艺条件为：加水量为药材量的３０倍，浸泡３ｈ，提取 １５ｈ；茯苓、炙甘草、红参和法半夏以及上述药渣水提取工艺条件为：加水量为药材量的１５倍，浸泡４ｈ，每次煎煮３ｈ，煎煮３次；沸腾制粒的工艺条件为：稠浸膏：糊精＝２：１，稠浸膏相对密度１３０（２５℃测定），喷液电压１２０伏特，抖袋周期６５个（每个抖袋周期来回抖袋２次）。结论：所确定的工艺条件稳定可行。更多还原

【Abstract】 OBJECTIVE: To optimize the preparation process of Xiangsha Liujun Granule. METHODS: By the orthogonal design. taking the rates of recovery of volatile oil, Ginsenoside Re and qualified granules as the indexes, we optimized the oil extracting conditions, the decocting conditions and the conditions of granulation by spayer. RESULTS: The optimum oil ex- tracting conditions for four kinds of herbs(Pericarpium Citri Reticulatae etc.) were that water was 30 times of herbs in weight, soaking time was 3 hours and extracting time 15 hours. The optimum decocting conditions for four kinds of herbs(Fuling etc.) were that water was 15 times of herbs in weight, soaking time was 3 hours and decocting time 4 hours, herbs were decocted twice. The optimum conditions of granulation by sprayer were that the fliud extract was 2 times of Dextrin in weight, the rel- ative density of the fliud extract was 1. 30(measured at 25℃), the voltage of sprayer was 120 volts, the period of shaking bag was 65 times(shaking bag back and forth twice in each period). CONCLUSION: The results of the experiment make it clear that the preparation process of Xiangsha Liu jun Granule is stable and feasible.更多还原