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输卵管妊娠放射介入治疗的临床研究

Clinical research of radioactive interventional therapy for tubal pregnancy

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【作者】 李小毛侯红瑛范建辉陶淑芸黄怀筠朱康顺

【Author】 Li Xiaomao,Hou Hongying,Fan Jianhui,et al. The Third Affiliated Hospital,Sun Yet-sen University of Medical Sciences,Guangzhou 510630,China

【机构】 中山医科大学附属第三医院妇产科!(广州510630)中山医科大学附属第三医院介入科

【摘要】 目的 探讨输卵管妊娠放射介入治疗的临床疗效及适应证。方法 采用X线影像监视下选择性子宫动脉内插管 ,一次性灌注MTX 5 0mg或MTX 80mg加 5 -FU 5 0 0mg ,并辅以明胶海绵颗粒栓塞治疗输卵管妊娠 2 8例 ,观察其症状、体征、血尿 β -hCG及B超结果的变化情况。 结果  2 5例输卵管妊娠经介入治疗成功 ,治愈率为 89 3%。腹痛症状于介入治疗后 5 17天内消失 ,阴道流血症状于介入治疗后 313天内消失。血、尿β -hCG于介入治疗后 3周内转为阴性。B超检查盆腔液性暗区 80 %于介入治疗后 2周内消失 ,附件包块 88%于介入治疗后 4周内消失。结论 未破裂型输卵管妊娠或破裂型与流产型输卵管妊娠但无明显贫血和休克征象的患者采用放射介入治疗是有效的

【Abstract】 Objective To study the clinical effects and indication of the radioactive interventional therapy for tubal pregnancy.Methods 28 tubal pregnancy cases were treated with selective intubation,one-shot perfusion MTX 50mg or MTX 80mg+5-FU 500mg,combined with gelfoam particles embolization via uterine artery with the help of X-ray image.The change of symptoms,signs,β-hCG in blood and urine,results of B-Ultrasonogram were observed.Results 25 cases were treated successfully,the curative rate was 89 3%.After interventional therapy,abdominal pain disappeared in 5~17 days,vaginal bleeding released in 3~13 days.The β-hCG in blood and urine couldn’t be examined in 3 weeks.The liquid in the pelvic cavity of 80% cases disappeared in 2 weeks,while the mass of 88% cases disappeared in 4 weeks through B Ultrasonogram.Conclusion The radioactive interventional therapy is effective for unruptured tubal pregnancy and ruptured or aborted tubal pregnancy without marked anemia or shock.

  • 【文献出处】 中国实用妇科与产科杂志 ,Chinese Journal of Practical Gynecology and Obstetrics , 编辑部邮箱 ,2000年12期
  • 【分类号】R714.2
  • 【被引频次】27
  • 【下载频次】86
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