【摘要】 目的: 研究新生儿多脏器损伤的机理, 提供早期诊断方法。方法: 应用Ultram ark-9 (HDI) 彩色超声诊断仪等研究同一窒息儿脑、肾、胃肠血流动力学和心脏功能的变化。结果: (1) 新生儿窒息后各脏器血液灌流量均减少, 但程度不一致, 以肠道最先受累且程度最重恢复最慢; (2) 心功能障碍是窒息的常见并发症, 其特点是舒张功能首先受累, 收缩功能障碍则右室重于左室; (3) 低氧血症是新生儿窒息的病理生理基础, 且与各脏器损伤的程度具有高度的相关性。结论:(1)血流动力学紊乱,血流量尤其舒张期血流量减少是新生儿窒息各脏器损伤的主要原因;(2) 新生儿在应激状态下不但生命与非生命器官间, 且在不同的非生命器官之间亦存在着血流再分布; (3) 超声检测各脏器血流动力学变化, 可用于新生儿窒息多脏器损伤的早期诊断。更多还原

【Abstract】 Objective:To study the pathogenesis of multiple organs in asphyxiated neonates and to offer early diagnostic methods.Methods:The changes of hemodynamics of brain,kidney,gastrointestinal tract and heart function in thirty asphyxiated newborn infants were examined by using Ultramark 9 ultrasonography.Results:(1)The blood perfusion of organ involved was decreased with different degree;(2)Cardiac dysfunction was the common complication,right ventricular systolic dysfunction was dominated.The diastolic dysfunction appeared earlier than systolic dysfunction;(3)The hypoxemia was the important pathophysiologic basis of the organ damage and significantly correlated with the degree of the organs involved.Conclusion:Neonatal asphyxiated will induce hemodynamic disturbance of many organs including the heart.更多还原