【摘要】 采用正交试验浓度加倍的方法 ,进行了农抗 12 0发酵培养基筛选 ,获得两种培养基配方Q1和Q2 。经摇瓶发酵试验 ,发酵水平分别比原始配方提高了 197 3%和 130 9%。摩式自动控制发酵罐试验 ,发酵水平是原始配方的 32 7%和 181%。 2 0M3发酵罐中试 ,发酵水平比原始配方提高了 30 0 0～ 50 0 0单位。更多还原

【Abstract】 High yield fermentation medium of agro antibiotic 120 had been optimized by double dose method.The formulas of medium Q1 and Q2 show higher production than original fermentation medium:The production of toxic potency was 197 3% and 130 9% higher than original fermentation medium in shaker of fermentation.The producation of toxic potency was 327% and 181% of that of original fermentation medium in auto fermentation testing.The toxic potency unit was 3000-5000ITU/mg higher than original fermentation medium in fermente with a capacity of twenty tons.更多还原