【摘要】 目的 :研究舍尼通治疗良性前列腺增生症 (BPH)的疗效。方法 :对门诊 67例患者分组 ,舍尼通组 3 7例单用舍尼通治疗 ,联合用药组 3 0例应用舍尼通和特拉唑嗪治疗。结果 :舍尼通组治疗 10个月后症状评分和前列腺体积均有明显改善 (P <0 .0 5 ) ,而尿流率、残余尿量和生存质量评估无明显好转。联合用药组治疗 2个月后最大尿流率和残余尿量有明显改善 (P <0 .0 5 ) ;治疗 10个月后尿流率有进一步改善 ,但前列腺体积和生存质量评估无明显变化。结论 :舍尼通治疗BPH作用缓和 ,适用于轻、中度患者 ,但并不推荐和特拉唑嗪联合应用更多还原

【Abstract】 Objective:To study the efficacy of cernilton in the treatment of benign prostatic hyperplasia (BPH). Methods:In 67 cases of outpatients, 37 patients were treated with cernilton alone for 10 months, 30 patients were treated with cernilton combined with terazosin. Results:Symptom scores and prostatic volume of 37 patients decreased significantly from baseline (P< 0.05 ), but there were no change in urine flow rate, residual urine volume and quality of life. The results of 30 patients indicated that the symptom scores and residual urine volume were significantly reduced, and peak flow rate was significantly improved 2 months after treatment (P< 0.05 ). At the end of 10 months, there was a more decrease in the urine flow rate in the combined drugs group, but there were no significant difference in either prostatic volume or quality of life. Conclusion:It is showed that cernilton has a mild beneficial effect in patients with mild and moderate symptoms of BPH, however, terazosin is not recommended as a combined drug.更多还原