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慢性阻塞性肺病血小板聚集功能的观察
Investigation of Platelet Aggregation Function in Chronic Obstruction Pulmonary Disease
【摘要】 目的通过测试临床各种慢性阻塞性肺病(COPD)病人血小板聚集功能(PAG),来探讨COPD与血小板聚积功能的关系。病例和方法临床上肺气肿26例,慢性支气管炎10例,哮喘4例,共40例。按临床专业会议诊断标准诊断为COPD,男26例,女14例,平均年岁分别为63.7±10.7岁和64.4±9.6岁。按Born法用MG-176型血小板聚集仪测定原发性聚集率(1分钟聚集率A1)和继发性聚集率(最大聚集率Amax)。结果 40例病人中A1 35%低下,17.5%升高(亢进),而Amax较对照组有显著性差异,提示急性发作期血小板功能低下,PAG紊乱。
【Abstract】 Aim This study is attempt to explore the relationship between platelet aggregation and chronic obstruction pulmonary disease via detennination of platelet aggregation function from practice medicine. Case and Method Collection of 40 patients, including pulmonary emphysema 26 cases, chronic bronchitis 10 case and asthma 4 case, have been recognized as COPD based on clinical diagnosis criteria for COPD which is made by an authorized associatiion. All of them covers 26 male patients (63 . 7 ± 10, 7 year old) and 14 female patients (64. 4 ± 9. 6 year old) . The primary aggregation rate (the first phase - aggregation rate A1 for first 1 min) and secondary aggregation (the second phase - the maximum aggregation rate Anax for 5 min) were measured by Born method. Result A1 of 35 % patients was declined and 17 . 5 % was en-hanced, Amaxim of COPD prone to decrease as compare with healthy objects as a control. Those suggest that the platelet function in COPD is declined and platelet aggregation function (PAG) presents disturbance
- 【文献出处】 医学研究通讯 ,Bulletin of Medical Research , 编辑部邮箱 ,2000年10期
- 【分类号】R563.9
- 【下载频次】17