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非蛋白氨基酸对生物活性多肽的修饰及其构效关系的研究进展
Progress in Modification of Bioactive Peptides with Non-protein Amino Acids and Their Application in the Studies of Structure - Activity Relationship
【摘要】 简述了非蛋白氨基酸的结构特征和生理活性。介绍了某些天然存在的含非蛋白氨基酸的生物活性肽及非蛋白氨基酸残基在相应活性肽中的重要作用。着重总结了非蛋白氨基酸对生物活性肽进行修饰的方式和构效关系研究的进展。
【Abstract】 The diversity of structure and physiological activity of non - protein amino acids is briefly described. Some peptides containing non - protein amino acid residues are introduced and the essential roles of these residues are discussed. Recent progress in modifying the bioactive peptides with non - protein amino acids and their preferences are generally reviewed.
【关键词】 非蛋白氨基酸;
构效关系;
激动剂;
拮抗剂;
生物活性肽类似物;
【Key words】 non-protein amino acids; relationship of structure and activity; agonist; antagonist; peptide anologues;
【Key words】 non-protein amino acids; relationship of structure and activity; agonist; antagonist; peptide anologues;
- 【文献出处】 有机化学 ,Chinese Journal of Organic Chemistry , 编辑部邮箱 ,2000年03期
- 【分类号】O621
- 【被引频次】27
- 【下载频次】509