【摘要】 目的 :本文主要观察溶栓灌注对QT间期及其离散度 (QTdispersion ,QTd)的影响。 方法 :测定 37例心肌梗死 ,患者的QT >440ms及QTd >5 0ms的患者比例分别为 41%及 5 7%。用尿激酶 37例 ,剂量 10 0万～ 15 0万u ,溶栓后再通 17例 ,未通 2 0例。结果 :37例溶栓后 2周再通组QTmax(36 1± 2 8、417± 32 ,P <0 0 5 )显著较未通组小 ,QTd为 5 1± 18、72± 32 ,与未通组有较显著差异 (P <0 0 5 )。结论 :成功的溶栓治疗主要是通过对复极的影响来缩短QT间期及降低QTd。提示QTd可作为判断预后的独立参数更多还原

【Abstract】 Objective:To dosewe the effect of thrombolytic reperfusion on QTc and QTd.Methods:37 patients with AMI are tested.These patients with QTc>440ms are 41% and those ones with QTd>50ms are 57% in this group. Thrombolytic patency patients are 17 and that no-patency ones 20 after giving them a dose of intravenous 1 0～1 5×106 uurokinase.Results:Two weeks later,QTc is shorter in thrombolysis with patency group (QTc max 361 28ms) than in that with non-pateney group (QTc 417 32ms),There is an obvious QTd difference between patency group and non-patency group.Conclusion:A successful thrombolytic treatment chiefly acts on myocardial repolarization to shorter QTc and QTd,so QTd can be an independent parameter to judge prognosis.更多还原