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特比萘芬软膏治疗浅部真菌病临床试验

A clinical trial of terbinafine ointment in treatment of superficial mycosis

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【作者】 张文娟肖德秀刘彦梅朱铁君

【Author】 ZHANG Wen Juan, XIAO De Xiu, LIU Yan Mei, ZHU Tie Jun (Department of Dermatology, The people’s Hospital of Beijing Medical University, BEIJING 100044, China) [

【机构】 北京医科大学人民医院皮肤科!北京100044

【摘要】 目的 :评价特比萘芬软膏治疗浅部真菌病的疗效和安全性。方法 :2 0 2例浅部真菌病病人 (男性 12 7例 ,女性 75例 ;年龄 36a±s 12a)用特比萘芬软膏均匀涂布患处bid。体、股癣 ,花斑癣治疗 1wk ;鳞屑水疱型手、足癣治疗 2wk ;鳞屑角化型手、足癣治疗 4wk。结果 :总有效率为 91.1% ,真菌清除率 95.5%。不良反应发生率 2 %。结论 :特比萘芬软膏治疗浅部真菌病疗效显著且安全。

【Abstract】 AIM: To evoluate the efficacy and safety of terbinafine ointment in the treatment of superficial mycosis. METHODS: Two hundred and two patients (M 127, F 75; age 36± s 12) with superficial mycosis were treated with terbinafine ointment (given thinly on the suface 2 times daily). The patients with tinea corporis, cruris or versicolor were treated for 1 wk. The patients with tinea manum or pedis of squamus and vesiclar type were treated for 2 wk. The patients with tinea manum or pedis of squamous hyperkeratotic type were treated for 4 wk. RESULTS: The total excellent response rate of terbinafine ointment was 91.1%, clearance rate of fungi was 95.5%. The adverse reaction rate of terbinafine ointment was 2%. CONCLUSION: Terbinafine ointment is a effective and safe drug in treating superficial mycosis.

【关键词】 特比萘芬皮肤真菌病临床试验软膏
【Key words】 terbinafinedermatomycosesclinical trialointment
  • 【文献出处】 中国新药与临床杂志 ,CHINESE JOURNAL OF NEW DRUGS AND CLINICAL REMEDIES , 编辑部邮箱 ,2000年S1期
  • 【分类号】R978.5
  • 【被引频次】3
  • 【下载频次】49
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