节点文献

L-精氨、5-氟脲嘧啶对艾氏腹水癌鼠的治疗分析

The analyses of therapy of EAC mice with L-Arg and 5-Fu

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 李宛青张静吴爱群

【Author】 LI Wan-qing 1,ZHANG Jing 2,WU Ai-qun 2 (1.Zhengzhou Education University,Zhengzhou 450002,China; 2.Dep of Anatomy,Henan Medical University,Zhengzhou 450052,China)

【机构】 郑州教育学院生物科!河南郑州450052河南医科大学解剖教研室!河南郑州450052

【摘要】 将 1 0 0只小白鼠制成 EAC模型鼠 ,随机分成四组 ,分别向腹腔注射 L-精氨酸、5-氟脲嘧啶、L-精氨酸 +5-氟脲嘧啶、生理盐水 ,同时记录各组小鼠自然存活时间、处死时平均腹水量、每毫升腹水中肿瘤细胞数、接种 EAC细胞两周后平均体重 .以探讨 L-精氨酸、5-氟脲嘧啶对艾氏腹水癌 (EAC)小鼠的治疗效果 .实验结果显示 :L-精氨酸 +5-氟脲嘧啶组小鼠自然存活时间最长 ,无腹水 .说明两者联合使用具有一定抗癌作用 ,而且延长了 EAC小鼠的存活时间 ,对机体的免疫力有所提高 ,同时也提高了小鼠的存活质量

【Abstract】 mice were divided into four groups randomly,each group including 25 mice which would be inoculated EAC (Ehrlich ascites carcinom a)cells.The mice were treated by celiac injection L-Arg,5-Fu,L-Arg+5-Fu,sali ne solution,separa tely.To investigate the effects of L-Arg and 5-Fu on the EAC mice,the survival t ime,the average hydroperitoneum capacity when the mice were killed,the average w eight of the mice inoculated EAC cells after two weeks were recorded for each gr oup.The result shows that the group with L-Arg+5-Fu survived the longest time without hydroperitonum,and also shows that the two physics were used united can enhances mice’s antineoplastic ability,and prolong mice’s survial time,increas e its survival quality.

【关键词】 L-精氨酸5-氟脲嘧啶治疗EAC
【Key words】 L-Arg5-FutherapyEAC
【基金】 河南省科技攻关项目!(971 2 0 0 2 72 )
  • 【文献出处】 信阳师范学院学报(自然科学版) ,JOURNAL OF XINYANG TEACHERS COLLEGE(NATURAL SCIENCE EDITION) , 编辑部邮箱 ,2000年03期
  • 【分类号】R73-36
  • 【下载频次】17
节点文献中: 

本文链接的文献网络图示:

本文的引文网络