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锌对血液流变性的影响

THE EFECTS OF ZINC ON HEMORHEOLOGICAL PARAMETERS

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【作者】 田福宏韩春英杨晓霞边建朝王林相有章

【Author】 Tian Guhong , Han Chunying ,Yang Xiaoxia et. al (Jinan No. 1 Hospital, Shandong 250014)

【机构】 山东省济南市第一人民医院山东省地方病防治研究所!济南250014

【摘要】 目的:探讨锌对血液流学指标的影响。方法:采用新西兰大白兔饮水中加葡萄糖酸锌(锌含量150.0mmol/L)喂养,设正常组对照,满12个月后取血测定血液流变学各指标。结果:加锌组较对照组全血粘度(高切、中切、低切)及血浆粘度明显升高(P<0.05~0.01),凝血酶原时间缩短(P<0.01),胆固醇、甘油三酯及血糖升高(P<0.01),红细胞沉降率增快(P>0.05)。结论:锌可能通过干扰脂代谢引起血液粘度增加,合理用锌对子防治缺血性心脑血管病有重要意义。

【Abstract】 Cbjective: To study the effects of zinc on hemorheological. Methods: 20 New Zealand white rebbits were divided into 2 groups. (control group and glucose zinc supplemental group). Hemorrheological of parameters all rabbits in glucose zinc supplemental group were determined after they were fed with water of glucose zinc (150. 0 mmol/L). Results: Compared with the rabbits in control group whole blood viscosity, plasma viscosity, bind lipids and blood glucose were increased significantly (p < 0. 05 - 0 .01 ), prothormbin time was shorted (p < 0 .91 ) and erythrocyte sedimentation offerd rate was speeded. (p < 0.01), but qantity and quality cells were not changed (p > 0.05) in the rabbits of zinc supplemental group. Conclusion: Zinc may result in increased blood viscosity by interfering lipid metabolism, thus the suitable use of zinc is very significant for the prevention and treatment of diseases on heart, brain and blood vessel.

【关键词】 血液流变学血粘度血脂
【Key words】 Zinc Hemorrheology Blood viscosity Blood lipid
【基金】 山东省卫生厅科研基金
  • 【文献出处】 中国血液流变学杂志 ,Chinese Journal of Hemorheology , 编辑部邮箱 ,2000年02期
  • 【分类号】R151
  • 【被引频次】2
  • 【下载频次】24
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