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血液剪切对红细胞变形性的影响

EFFECTS OF ERYTHROCYTE DEFORMABILITY ON THE SHEAKING OF BLOOD

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【作者】 徐宗佩张伯礼王益民张吉正官涛李百臣

【Author】 Xu Zongpei, Zhang Boli , Wang Yimin ,Zhang Jizheng (DPR of Korea) Gong Tao, Li Baichen(Taiwan) (Traditional Chinese Medicine Engineering and Research Institute of Tianjin University of TCM Tianjin 300193)

【机构】 天津中医学院中医工程研究所!天津300193天津中医学院中医工程研究所!天津300193 朝鲜天津中医学院中医工程研究所!天津300193 台湾

【摘要】 检测0~ 1000s-1切变率条件下大鼠和小鼠红细胞变形指数(DI值)的变化,结果发现:(1)DI值随切变率升高而递增。(2)大鼠在切变率为500s-1以下时,DI值随切变率升高显著递增,500s-1以下各组间DI值有显著或非常显著差异,各组与500s-1以上各组间DI值也有显著或非常显著差异;小鼠在切变率为400s-1以下时, DI值随切变率升高显著递增,400s-1以下各组间 DI值有显著或非常显著差异,各组与 400s-1以上各组间 DI值也有显著或非常显著差异。(3)大鼠在切变率为 500s-1以上时,DI值随切变率升高递增,但无显著差异;小鼠在切变率为 400s-1以上时,DI值切变率升高递增,亦无显著差异。提示在切变率为500s-1或400s-1以上时,DI值接近极限。(4)不同种生物,红细胞易变形的切变率范围各异。

【Abstract】 Ektacytometer type LG-B-190 was used to check up the condition of change of the index(DI value) of erythrodegeneration in rats and mice in the shear rate rang of 0-1000S-1 / The results indicated that; 1. DI value increased progressively as the shear rate rose. 2. In case the shear rate in rats was lower than 500S-1 ,the DI value increased remarkably as the shear the rose. In case the shear rate in mice was lower than 400S-1 , the DI value increased considerably with the rise of the shear rate. 3. In case the shear rate in rats was higher than 500S-1 , the DI value increased progressively with the rise of the shear rate but had not marked difference; in case shear rate in mice was higher than 4000S-1, the DI value increased progressively as the shear rate grew but had not marked difference, either. 4.According to different species of animals, the range of the shear rate of easily-degenerating erythrocyte was not the same.

  • 【文献出处】 中国血液流变学杂志 ,Chinese Journal of Hemorheology , 编辑部邮箱 ,2000年02期
  • 【分类号】R318.01
  • 【被引频次】10
  • 【下载频次】148
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