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针刺对变应性鼻炎患者血浆内皮素及鼻粘膜微血管的影响

The effect of acupuncture on the plasmic endothelind and the nasal mucosal microvessels or allergic rhinitis patients

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【作者】 陈舒华汪宗文梅丽容邹艳黄绍云

【Author】 Chen Shuhua, Wang Zhongwen,Mei Lirong,et al (Department of Otolaryngology, The 2nd hospital of Foshan,Guangdong 528000)

【机构】 广东省佛山市第二人民医院耳鼻咽喉科!(528000)

【摘要】 目的对33例常年性变应性鼻炎患者进行针刺治疗,以观察其对血浆内皮素(endothelin,ET)及鼻粘膜微血管的影响。方法①血浆ET测定:采用特异性放射免疫法(均相竞争法)直接测定血浆ET含量。②鼻粘膜微血管的观察:主要观察鼻粘膜微血管管径、管袢数及鼻粘膜微血管的形态。③针刺治疗:选择曲池、血海两穴进行针刺。结果变应性鼻炎患者鼻粘膜微血管管径针刺后较针刺前增粗;针刺后变应性鼻炎患者鼻粘膜微血管形态变化以灯丝状微血管增多、网络状微血管减少为特征;变应性鼻炎患者鼻粘膜微血管管袢数针刺后较针刺前增多;变应性鼻炎患者针刺后血浆ET含量明显降低。结论变应性鼻炎针刺后鼻粘膜微循环明显改善,表现为鼻粘膜微血管管径增粗,灯丝状微血管增多、网络状微血管减少,管拌数增加,并与血浆ET存在密切关系,其机理可能是通过降低血浆ET的水平而起作用的。

【Abstract】 Objective To understand the effect of acupuncture on the endothelin of plasma and the nasal mucosal microvessels in 33 patients with allergic rhinitis treated with acupuncture. Method Endothelin had been assaied with RIA. Nasal microvessels had been observed with nasal mucosal microcirculation microscopy. Acupuncture treatment was selected on point of Quchi and XueHai. Results The nasal mucosal microvascular diameter after acupuncture became widen than before. The nasal mucosal microvascular morphological changes after acupuncture were characterized by increase of filament like microvessels and decrease of network like microvessels. The numbers of the microvascular loop were increas after acupunture. The content of endothelin in patients with allergic rhinitis lowered down after acupuncture treatment. Conclusion The result indicates that the nasal microcirculation has been improved distincly after acupuncture and closely relates with endothelin.

【基金】 本课题由国家自然科学基金;广东省卫生厅科学基金青年基金资助课题!(39200163)
  • 【文献出处】 中国中西医结合耳鼻咽喉科杂志 , 编辑部邮箱 ,2000年05期
  • 【分类号】R765
  • 【被引频次】27
  • 【下载频次】105
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