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夏枯草中苯丙素和三萜的分离和鉴定(英文)

A New Phenylpropanoid and Triterpenoids from Prunella vulgaris

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【作者】 王祝举赵玉英王邠郦皆秀艾铁民陈雅妍

【Author】 Wang Zhuju, Zhao Yuying*, Wang Bin, Li Jiexiu, Ai Tiemin and Chen Yayan Department of Natural Medicines, Beijing Medical University, Beijing 100083

【机构】 北京医科大学天然药物学系!北京 100083

【摘要】 从夏枯草中用色谱法分离得到1 个新的苯丙素类化合物1 和5 个已知的三萜类化合物2~6, 经波谱法和化学法鉴定为3,4?a-三羟基苯丙素丁酯1 ?a,?a,24-三羟基乌苏-12,20(30)-二烯-28-酸(2) ?a,?a,24-三羟基齐果-12-烯-28-酸(3)?a,?a,24-羟基乌苏-12-烯-28-酸(4) ?a,?b-二羟基齐墩果-12-烯-28-酸(5)和?a,?b-二羟基乌苏-12-烯-28-酸(6) ,5 个三萜类化合物均为首次从夏枯草中分离得到。

【Abstract】 A new phenylpropanoid (1) together with five known triterpenoids were isolated from the spikes of Prunella vulgaris. Their structures were established on the basis of spectral analysis as 3,4,a-trihydroxy-butyl phenylpropionate (1), ?a,?a,24-trihydroxyursa-12,20(30)-dien-28-oic acid (2), ?a,?a, 24-trihydroxyolean-12-en-28- oic acid (3), ?a,?a,24-trihydroxyursa-12-en-28-oic acid (4), ?a,?b-dihydroxyolean-12-en-28-oic acid (5) and ?a,?b-dihydroxyursa- 12-en-28-oic acid (6). Five triterpenoids were isolated from this plant for the first time.

  • 【文献出处】 Journal of Chinese Pharmaceutical Sciences ,中国药学(英文版) , 编辑部邮箱 ,2000年03期
  • 【分类号】R284
  • 【被引频次】12
  • 【下载频次】280
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