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猪支原体肺炎免疫试验

Immunity test on mycoplasmal pneumonia of swine

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【作者】 张道永林毅邓小东冯金传杨晓梅王文贵李力张先惠曾惠

【Author】 ZHANG Dao yong,LIN Yi,DENG Xian dong,et al (Sichuan Academy of Animal Sciences,Chengdu 610066,China)

【机构】 四川省畜牧科学研究院!中国成都610066四?

【摘要】 用无支原体肺炎病猪场的哺乳仔猪 1 1窝共计 1 0 7头 ,分为 4组 ,1组 2 6头猪 ,按疫苗生产厂的免疫方法 ,于 1 5日龄胸腔注射弱毒疫苗 2头份 ;2组 2 6头猪 ,在 1 5日龄时胸腔注射弱毒疫苗 1头份 ,2周后肌肉注射灭活疫苗 1头份 ;3组2 7头猪 ,按疫苗生产厂免疫方法于 1 5日龄和 30日龄肌肉注射灭活疫苗各 1头份 ;4组 2 8头 ,不注射猪支原体肺炎疫苗以作对照。在接种疫苗后 ,分别于 1 2 0天、1 80天、 2 40天进行同居感染和攻毒试验。经临床检查 ,X线胸透结果表明 ,第 2组在 1 5日龄首免弱毒活苗 ,2周后二免灭活苗的免疫保护率最高 ,2 40天的免疫保护为 91 7% ,比 1组和 3组两种常规免疫法的保护率 (75 %和 6 6 7% )分别提高1 6 7和 2 5个百分点。对猪支原体肺炎IHA抗体的监测结果也同样表明 ,第 2组的免疫效果最好 ,2 40天的IHA抗体阳性检出率为 1 0 0 % ,而 1组和 3组均为71 4%。

【Abstract】 healthy pigs were divided into four groups in this test.No 1 group including 26 pigs were injected attenuated vaccine (2 dose) at 15 days old.No 2 group including 26 pigs were injected attenuated vaccine(1 dose) at 15 days old and injected inactivated vaccine(1 dose) after two weeks.No 3 group including 27 pigs were injected attenuated vaccine(1 dose) an 15 days old and 30 days old,respectively.No 4 group including 28 pigs injected without any vaccine were used to the control.At 120,180,240 days after vaccination,these pigs were challenged with My Suipneumonia .The protective rates in No 2,No 1,No 3 group were 91 7%,75% and 66 7% 240 days after inoculation,respectively.The IHA test showed that the positive rate of serum antibody in No.2 group was also the highest.

【关键词】 免疫疫苗猪支原体肺炎
【Key words】 lmmunizationvaccinemycoplasmal pneumonia of swine
【基金】 国家“九·五”重点攻关项目
  • 【文献出处】 西南农业学报 ,SOUTHWEST CHINA JOURNAL OF AGRICULTURAL SCIENCES , 编辑部邮箱 ,2000年S1期
  • 【分类号】S852.4
  • 【被引频次】10
  • 【下载频次】177
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