【摘要】 该研究采用胚胎期药物注射法和小鸡一次性被动回避反应行为模型，观察了皮质酮和地塞米松对暗孵化小鸡记忆的影响，以及两类皮质激素受体颉颃剂RU-486和Spironolactone对光照以及皮质酮效应的阻断作用。结果表明，糖皮质激素可明显改善暗孵化小鸡的记忆；两类受体颉颃剂均阻断了光照和皮质酮对暗孵化小鸡记忆的改善作用，但糖皮质激素受体对小鸡记忆的作用是特异性的，盐皮质激素主要通过对小鸡的基本状态的改变来影响记忆活动。因此，糖皮质激素及其受体系统参与了光照对小鸡记忆的作用过程。更多还原

【Abstract】 The effect of two kinds of corticosleroids: corticosterone and dexamthesone on memory retention of dark hatched chicks and corticosteroid receptor antagonist RU- 486 and Spironolactone on memory retention improved by light exposure or corticostorone were examined using one-trial passive avoidance model in chicks. It showed that corticosterone and dexamthesone markedly improved memory retention of dark hatched chicks respectively. RU-486 and Spironolactone blocked memory retention improved by light exposure or corticosterone administration in chicks. But the effect of glucocorticoid receptor was specific, however minerocorticoid mainly affected the general state of the chicks. Thus, glucocorticoid and its receptors were involved in effect of light exposure on memory in chicks.更多还原