【摘要】 [目的]研究盆腔检查(PE)、超声检查(US)及血清CA125水平在鉴别卵巢良恶性包块方面的作用及3项检查联合应用的价值。[方法]对拟手术治疗的卵巢包块患者在术前均行PE ,US及血清CA125测定。[结果]绝经前妇女中8 5 %(11/130)为卵巢恶性肿瘤 ,绝经后妇女中36 3 %(29/80)为卵巢恶性肿瘤 ,PE的敏感性、特异性、阳性预测值、阴性预测值及准确性的百分率分别为62 5 %、82 4 %、45 5%、90.3 %及78 6% ;CA125的上述诊断指数分别为85 0 %、80 6 %、50 7 %、95 8%及81 4 % ;US的上述诊断指数分别为95 0%、94 1%、79 2%、98 8 %及94 3 %。在3种检查方法中 ,US的各项指数最好 ,尤其是在绝经后妇女。如果3项检查均为阴性 ,则所有患者的卵巢包块均为良性 ;如3项检查均为阳性 ,则95.2 %患者卵巢包块为恶性。[结论]PE、血清CA125测定及US在术前诊断卵巢包块良恶性方面均有一定作用 ,但是他们也都有各自的不足 ,如三者联合应用则在鉴别卵巢包块良、恶性方面具有更大价值。更多还原

【Abstract】 To study pelvic examination (PE),ultrasonography (US) and determination of serum CA125 on differential diagnosis of patients with benign or malignant ovarian masses. Patients with ovarian masses were studied by prospective analysis.All patients were investigated with PE,US and determination of serum CA125 before operation. In 130 premenopausal females,8 5%(11/130) was malignant ovarian tumors,and in 80 postmenopausal females,36 3%(29/80) was malignant ovarian tumor.The sensitivity,specificity,positve predictive rate,negative predictive rate and accurate rate of PE were 62 5%,82 4%,45 5%,90 3% and 78 6%,respectively.Correspondingly,diagnostic rates of CA125 above mentioned were 85 0%,80 6%,50 7%,95 8% and 81 4%,respectively,and about TVS were 95 0%,94 1%,79 2%,98 8% and 94 3%,respectively.In the three assays the diagnostic rate of US was best especially in postmenopausal females. If the three assays combined and showed negative, all the masses were benign.If those all showed positive ,95 2% masses were malignant.[Conclusions]PE,serum CA125 determination and US in preoperative diagnoses of benign or malignant ovarian masses all revealed certain effects,but they have their own defects.If 3 assays combine,it may show higher value.更多还原