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补骨脂素与维甲酸联合应用对Mc3细胞膜表面四种凝集素受体表达的影响
Agglutinin receptor effects of 8-MOP combined with ATRA or alone on Mc3 cells
【摘要】 目的 研究 8-MOP与ATRA联合应用对Mc3细胞膜表面凝集素受体表达的影响。方法 免疫组织化学染色方法。结果 对照组凝集素受体表达分别为 :PNA(+~ + + ) ,UEA(-~ + + ) ,SBA(+~ + + ) ,RCA(+~ + + ) ;8-MOP组凝集素受体表达分别为 :PNA(-~ + + ) ,UEA(+ ) ,SBA(+ ) ,RCA(+~ + + ) ;ATRA组凝集素受体表达分别为 :PNA(-~ + + ) ,UEA(+ ) ,SBA(+~ + + ) ,RCA(+ ) ;8-MOP +ATRA组凝集素受体表达分别为 :PNA(-~ + + ) ,UEA(+ ) ,SBA(-~ + ) ,RCA(+~ + + )。结论 PNA ,UEA ,SBA和RCA染色强度的下降或增高可能提示肿瘤倾向于良性分化
【Abstract】 Objective To study the agglutinin receptor effects of 8-MOP combined with ATRA or alone on Mc3 cells.Methods Cell immunohistochemical staining method.Results Four agglutinin rceptors expressions of control group were PNA(+~++),UEA(-~++),SBA(+~++) and RCA(+~++);those of 8-MOP group were PNA(-~++),UEA(+),SBA(+) and RCA(+~++);those of ATRA group were PNA(-~++),UEA(+),SBA(+~++) and RCA(+);those of 8-MOP combined with ATRA group were PNA(-~++),UEA(+),SBA(-~+) and RCA(+~++).Conclusion The decrease or increase of staining intensity of PNA,UEA,SBA and RCA may indicate benign differentiation of Mc3 cells.
【Key words】 methoxypsoralen All trans retinoic acid Mucoepidermoid carcinoma Agglutinin;
- 【文献出处】 现代口腔医学杂志 ,JOURNAL OF MODERN STOMATOLOGY , 编辑部邮箱 ,2000年04期
- 【分类号】R739.85
- 【被引频次】6
- 【下载频次】39