【摘要】 为探讨居民肝癌的主要危险因素以及各因素间的联合作用,采用病例对照研究方法,分析各因素的比值比以及因素之间的交互作用、归因交互百分比。结果显示乙肝病史、肿瘤家族史和易生气、有抑郁感、消极处世态度等因素可能是肝癌的危险因素。比值比(OR及95%CI)分别为18.26(4.40～75.77)、2.75(1.22～6.12)、1.67(0.92～3.06)、1.70(1.08～2.17)和2.00(1.20～3.23)。乙肝病史和肿瘤家族史、不良心理因素间的交互作用指数分别为1.65、1.16,归因交互百分比为38.4%和13.3%。提示乙肝病史与肿瘤家族史、不良心理因素之间存在正交互作用。更多还原

【Abstract】 To study the risk factors of primary hepatocellular cancer (PHC) and their interactions, a case control study with calculated odds ratios(OR) and synergy effects index(SI) was conducted. The history of hepatitis B, family histories of cancers and psychosocial factors were main risk factors of PHC, and their effects were positive and synergic. The SI between hepatitis B and family histories of cancers,psychosocial factors are 1 65 and 1 16 respectively.更多还原