【摘要】 以芦丁为标准品 ,采用紫外分光光度法 ,对用乙基纤维素等辅料制备的缓释片和用淀粉等辅料制备的银杏叶普通片 ,进行了银杏总黄酮含量测定和体外累积释药百分率的比较 .普通片的体外释药动力学为一级释放 ,缓释片在 2～ 1 2 h为零级释放 ,普通片释放 50 %的时间为 66min,缓释片释放 50 %的时间为 1 1 2 min,缓释片体外释药速率明显慢于普通片更多还原

【Abstract】 With the rutin as standard, and with UValso, the total flabonoides and of outbodyaccumulated percent of drugrelease have been tested for the slowedrelease tablets of ethylcellulose and filler. The release kinetics of general tablets is firstorder kinetics, slowedrelease tablets is zeroorder kinetics in the first 2~12 h. General tablets need 66 min for 50% release, but the release tablets need 112 min for 50%, furthermore, release rate is slower as the rate of general tablets of offbody.更多还原