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等离子喷涂HA/Ti复合涂层研究 Ⅱ.生物学性能
Plasma Sprayed HA/Ti Composite Coatings Ⅱ. Biological properties
【摘要】 对等离子喷涂 HA/Ti复合涂层进行模拟体液和体外细胞试验,以考察涂层的生物学性能,结果指出,涂层经模拟体液浸泡后,表面覆盖一层碳酸磷灰石(carbonate-apatite),这表明涂层具有良好的生物活性.粗糙的涂层表面易于形成碳酸磷灰石.模拟体液的浓度太小或PH值太大,均会导致碳酸磷灰石层不能在涂层表面形成.体外细胞试验显示,成骨细胞能在涂层表面紧密贴壁并正常生长,显示涂层具有优良的生物相容性.
【Abstract】 SBF test and cell culture in vitro were carried out to evaluate the biological properties of plasma sprayed HA/Ti composite coatings. Results obtained show that the coating surfaces will be covered by carbonate-apatite layer after being immersed in SBF for 1 day, which indicate that the composite coatings possess good bioactivity. Carbonate-apatite layer is inclined to form on the rougher coating surface. Low concentration and high PH value of SBF are harmful to the formation of carbonate-apatite layer. Excellent biocompatibility of the composite coatings can be confirmed by osteoblasts attaching firmly and growing well on the coating surface.
【Key words】 hydroxyapatite coating; HA/Ti composite coating; SBF test; cell cultuH;
- 【文献出处】 无机材料学报 ,Journal of Inorganic Materials , 编辑部邮箱 ,2000年06期
- 【分类号】TB33
- 【被引频次】20
- 【下载频次】180