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等离子喷涂HA/Ti复合涂层研究 Ⅱ.生物学性能

Plasma Sprayed HA/Ti Composite Coatings Ⅱ. Biological properties

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【作者】 郑学斌丁传贤王毅朱雅萍任一萍

【Author】 ZHENG Xue-Bin I DING Chuan-Xian, WANG Yi, ZHU Ya-Ping, REN Yi-Ping (Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China; Shanghai Institute of Traumatic Orthopedics, Shanghai 200025, China)

【机构】 中国科学院上海硅酸盐研究所!上海 200050上海市伤骨科研究所!上海200025

【摘要】 对等离子喷涂 HA/Ti复合涂层进行模拟体液和体外细胞试验,以考察涂层的生物学性能,结果指出,涂层经模拟体液浸泡后,表面覆盖一层碳酸磷灰石(carbonate-apatite),这表明涂层具有良好的生物活性.粗糙的涂层表面易于形成碳酸磷灰石.模拟体液的浓度太小或PH值太大,均会导致碳酸磷灰石层不能在涂层表面形成.体外细胞试验显示,成骨细胞能在涂层表面紧密贴壁并正常生长,显示涂层具有优良的生物相容性.

【Abstract】 SBF test and cell culture in vitro were carried out to evaluate the biological properties of plasma sprayed HA/Ti composite coatings. Results obtained show that the coating surfaces will be covered by carbonate-apatite layer after being immersed in SBF for 1 day, which indicate that the composite coatings possess good bioactivity. Carbonate-apatite layer is inclined to form on the rougher coating surface. Low concentration and high PH value of SBF are harmful to the formation of carbonate-apatite layer. Excellent biocompatibility of the composite coatings can be confirmed by osteoblasts attaching firmly and growing well on the coating surface.

【基金】 国家重点基础研究发展规划项目!(G1999064706);上海市新材料中心基金资助项目!(97JC14010)
  • 【文献出处】 无机材料学报 ,Journal of Inorganic Materials , 编辑部邮箱 ,2000年06期
  • 【分类号】TB33
  • 【被引频次】20
  • 【下载频次】180
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