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肝硬化患者亚临床肝性脑病的诱发电位检测

Evoked potentials in diagnosis of subclincal hepatic encephalopathy in cirrhotic patients

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【作者】 李建生高雯段红阳李书鑫

【Author】 Li Jiansheng; Gao Wen;Duan Hongyang; et al. (Department of gastroenterology,the first affiliated hospital Henan medical university,Zhengzhou, 450052)

【机构】 河南医科大学第一附属医院消化科!郑州450052河南医科大学第一附属医院神经外科实验室!郑州450052河南省电力医院河南医科大学第一附属医院神经内科实验室!郑州450052

【摘要】 目的了解不同严重程度肝硬化患者亚临床肝性脑病的发生率及其临床意义。方法对30例无临床肝性脑病的肝炎后肝硬化患者同时进行脑干听觉、视觉和短潜伏期体感诱发电位(BAEP、VEP、SSEP)检测。结果三种脑诱发电位检测以BAEP异常率(46.7%)高于 VEP和 SSEP(均为 36.7%);随着肝病程度加重,BM和 SSEP异常率逐渐增高,分别为 Child- Pugh A级41.7%和83%,B级46.7%和46.7%,C级66.7%和100%,而VEP则无此倾向。三种脑诱发电位异常的形式主要为波峰潜伏期延迟和波峰消失。结论脑诱发电位检测有助于肝硬化患者亚临床肝性脑病的诊断及预后判断,对临床肝性脑病的预防亦有一定的指导意义。

【Abstract】 Aim To evaluate the prevalence of subclinical hepatic encephalopathy (SHE) in hospitalized cirrhotic patients with different seventy. Method Brain stem auditory, visual and short -- latency so,aomatosensory evoked potentials (BAEP, VEP, SSEP) were examined in 30 cirrhotic patients without overt hepatic encephalopathy. Results The abnormality was more frequently detected by BAEP (46. 7% ) than by VEP and SSEP (both were 36. 7% ). The abnormal rates were correlated with the seventy of the liver disease in BAEP and SSEP: Child - Pugh class A patients were 41. 7% and 8. 3 %, class B patients both were 46 .7%, and class C patients were 66. 7% and 100%, respectively. But, there was no such tendency in VEP. The Main forms of abnormality were prolonged latency of the waves or decreased, even disappeard amplitudes. Conclusion Exdrination of brain evoked potentials is helpful for the detection of SHE and estimation of the prognosis in cirrhotic patients .

  • 【文献出处】 胃肠病学和肝病学杂志 ,Chinese Journal of Gastroenterology and Hepatology , 编辑部邮箱 ,2000年03期
  • 【被引频次】1
  • 【下载频次】33
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