【摘要】 目的:报道肥厚性梗阻型心肌病(HOCM)经双腔起搏治疗后的中、远期随访结果。方法:对11例已明确诊断,经双腔起搏治疗后取得良好血液动力学效果和临床症状改善的HOCM患者,在平均40个月后随访临床症状,并对其中9例复查了血液动力学指标,并与起搏治疗前后进行比较、分析。结果:11例患者中1例发生猝死,9例复查血液动力学指标显示仍维持起搏治疗之初的状态。存活的10例患者临床症状及运动耐量虽已明显下降,但仍优于起搏治疗之前。结论:双腔起搏治疗HOCM是一种能够长期改善其血液动力学障碍的方法,能延缓病程发展、推迟症状恶化,并有减少猝死、延长生命的可能性。更多还原

【Abstract】 Objective:To report the medium and long-term follow-up results in patients with hypertrophic obstructive cardiomyo-pathy (HOCM) who were treated with dual-chamber pacing. Methods: Eleven patients who were clearly diagnosed of HOCM were treated with dual-chamber pacing, and had achieved good hemodynamic effects and improved clinical symp-toms. We followed up their clinical symptoms after mean time of 40 months, re-checked 9 of them with hemodynamic in-dex,compared the results of pre-and post-pacing and analyzed them. Results:One of the 11 patients died of sudden death. Hemodynamic indexes of 9 re-checked patients remained at the level just after pacing. The clinical symptoms and sport en-durance of 10 survival patients significantly decreased,but were still better than those before pacing treatment. Conclusion: Dual-chamber pacing in patients with HOCM can improve their hemodynamic obstruction permanently, slow down patholo-gy development, postpone deterioration of the symptoms. It can reduce the occurrence of sudden death and prolong the life expectancy too.更多还原