【摘要】 为了了解血清前 S1抗原与 HBV DNA之间的关系 ,应用 EL ISA法对 2 2 9例 HBs Ag阳性患者血清前 S1抗原进行检测 ,并和 HBV DNA与 HBV检测结果作比较分析 ,结果表明 :前 S1抗原和具有病毒活动性复制意义的指标HBe Ag和 HBV DNA有一定相关 ,γ=0 .9812 ,可以较好地反映 HBV DNA的存在或复制情况。虽然它们之间的检测结果有相互关联 ,但所表达的临床意义并不完全一致 ,因此认为 :对不同类型 HBV感染患者前 S1抗原与 HBV和 HBVDNA的联合动态检测有助于临床诊断、疗效观察及预后判断更多还原

【Abstract】 To study the relationship between serum Pre S1 antigen and HBV DNA,serum Pre S1 antigen and HBV DNA marker in 229 patients positive for HbsAg were detected by using ELISA method and compared. It was found that both Pre S1 antigen and HbeAg were correlated with HBV DNA with the coefficient being 0.9812 and could be used to reflect the existence or reproduction of HBV DNA well. Although there was statistical correlation between them, their clinical implication was not completely the same. Therefore, a conclusion was drawn that combined detection of Pre S1 antigen, HBV and HBV DNA in the patients with different kinds of HBV infection was helpful to clinical diagnosis, therapeutic effect evaluation and prognosis judgement.更多还原