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氯磺丙脲及安妥明联合应用治疗脑外伤后尿崩症

Combined Use of Chlorpropamide and Clofibrade in the Treatment of Diabetes Insipidus Following Brain Trauma——A Report of 3 Cases

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【作者】 邸方王仲伟

【Author】 Di Fang 1, Wang Zhongwei 2 1 Department of Surgery, Wuhan Dongxihu People’s Hospital, Wuhan 430030 2 Department of Neurosurgery, The First People’s Hospital of Xinxiang City, Xinxiang 453000

【机构】 武汉市东西湖区人民医院外科!武汉430040河南省新乡市第一人民医院脑外科!新乡453000

【摘要】 为了探讨脑外伤后尿崩症的治疗 ,回顾性分析了 1982年以来收治的 2 0 0 0余例脑外伤患者 ,3例诊断为中枢性尿崩症。联用磺丙舒 (0 .1g,3次 / d)和安妥明 (1.0 g,2次 / d) ,3例患者尿崩症症状得到有效控制 ,取得满意疗效。讨论了磺丙舒和安妥明联合用药的机制及治疗中的注意事项

【Abstract】 In order to investigate the treatment of brain trauma induced diabetes insipidus, more than two thousand patients with brain trauma from 1982 were retrospectively analyzed. Among them, 3 cases were diagnosed as having central diabetes insipidus. All the 3 cases were subjected to the combined administration of chlorpropamide (0.1 g, 3 times a day) and clofibrate (1.0 g, 2 times a day). The symptoms for central diabetes insipidus were effectively controlled. The mechanism of combined use of chlorpropamide and clofibrade and the cautions in the treatment of central diabetes insipidus were discussed.

【关键词】 磺丙舒安妥明尿崩症脑外伤
【Key words】 chlaorpropamideclofibratediabetes insipidusbrain trauma
  • 【文献出处】 同济医科大学学报 ,ACTA UNIVERSITATIS MEDICTNAE TANGJI , 编辑部邮箱 ,2000年03期
  • 【分类号】R651.15
  • 【被引频次】3
  • 【下载频次】53
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