【摘要】 目的　探讨东莨菪碱合用葡萄糖酸钙快速治疗中重型急性氟乙酰胺中毒及其疗效机制。　方法　2 7例中重型急性氟乙酰胺中毒患者 ,行东莨菪碱及葡萄糖酸钙治疗 (治疗组 )。 1 6例中重型急性氟乙酰胺中毒患者 ,行解氟灵治疗 (对照组 ) ;观察抽搐停止、苏醒、心律失常恢复所需时间及治愈率。　结果　治疗组的上述症状较对照组的更快速控制、恢复 (P <0 .0 1 ) ;治疗组治愈率 1 0 0 % ,对照组治愈率 87.5%。　结论　东莨菪碱合用葡萄糖酸钙治疗急性氟乙酰胺中毒优于解氟灵对照组 ;东莨菪碱对病人的苏醒起主要作用 ;低钙是氟乙酰胺中毒引起抽搐的主要原因 ,很可能是心律失常的一个原因更多还原

【Abstract】 Objective To detect the rapid treatment for medium and serious FCH 2CONH 2 acut poisoning with 6541 and calcium crlucose and its mechanism of curative effect Methods 6541 and calcium cilucose were used to treat 27 medium and serious patients acutly poisoned by FCH 2CONH 2(called treatment unit),and acetamide to other 16 medium and serious patients(called compare unit)Observing the time of convulsion stopping awakearrthythmia recovery and the cure rate Results The above symptom of the treatment unit was faster controled and recovered than that of the compare unit(P<001)The cure rate of the treatment unit was 100%,and the compare was 875% Conclusion The effect of 6541 and calcium is superior to that of acetamideAwaking is largely belong to 6541Lower calium is main reason for convulsion caused by poisoning,and maybe a reason for arnthythmia too更多还原