【摘要】 探讨克罗米芬 (CC) /人绝经期促性腺激素 (HMG)单次用药联合方案 (简称小剂量刺激法 )在多囊卵巢综合征患者中的疗效。对 38例共 45个周期采用 CC5 0 mg/ d×5 d后单次给予 HMG1 5 0 IU的联合方案的卵泡发育情况、排卵及妊娠情况进行了监测 ,并与 CC 32例 43个周期相比较。结果小剂量组妊娠率 34% (1 3/ 38) ,周期排卵率 84%(38/ 45 ) ,卵巢过度刺激综合征 (OHSS)发生 1例 ;CC组妊娠率 1 2 % (3/ 2 4) ,周期排卵率5 6 % (2 4/ 43) ,OHSS1例。结果表明小剂量刺激法是一种安全有效的诱导排卵方案。更多还原

【Abstract】 To investigate the minimal stimulation effects of treatment with low dose clomiphene citrate (CC) and human menopausal gonadotropins (HMG) combination protocol in polycystic ovary syndrome (PCOS) patients. All cases were monitored by ultrasonography, cervical mucus, urine luteinizing hormone test and urine pregnancy test. Setting: The study was carried out in infertility clinic of the Fourth Affilated Hospital. Methods: Thirty-eight patients received 45 cycles of minimal stimulation (CC 50 mg/day for 5 days followed by a single dose of 150 IU HMG). Ovulatory rates ,pregnancy rates and the rates of complications were analyzed, and compared with those of a CC-alone protocol (32 patients underwent 43 cycles). Results: Ovulatory rates and pregnancy rates were different significantly (84%,34% for minimal stimulation versus 56%,12% for CC),but the rates of complications were similar. Conclusion: Minimal stimulation is a safe and effective regime for ovulation induction in PCOS patients.更多还原