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芍药甘草配伍化学变化研究

Chemical Changes of Compatibility of White Peony Root and Liquorice

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【作者】 王静蓉马琮瑜严永清朱丹妮

【Author】 WANG Jing rong, MA Cong yu, YAN Yong qing, ZHU Dan ni (Department of Complex Prescription of Traditional Medicine, China Pharmaceutical University, Nanjing,Jiangsu 210038, China)

【机构】 中国药科大学!江苏南京210038

【摘要】 对白芍药与甘草配伍水煎液进行了TLC分析,检查了芍药甙、甘草酸、甘草黄酮类成分的变化。进一步用HPLC方法测定了不同比例白芍与生甘草、炙甘草配伍后水煎液中芍药甙、甘草酸的含量。结果发现:与单味白芍水煎液相比,白芍与甘草以3∶1,2∶1比例配伍,芍药甙含量基本无变化;比例为1∶1时,芍药甙含量略有下降。甘草与芍药配伍后,甘草酸含量较单味甘草水煎液略低。HPLC检测发现配伍组水煎液沉淀中仅含微量芍药甙,基本不含甘草酸。

【Abstract】 Chemical changes due to compatibility of White Peony Root and Liquorice were studied preliminarily using TLC method. Paeoniflorin(PE), glycyrrhizie acid(GA) and flavonoids in Liquorice were examined respectively. HPLC method was further employed for determining content of PE and GA in different ratio compatibility groups. The results indicated that comparing with single Peony group PE content didn’t change in group of ratio 3∶1 and 2∶1 while reduced slightly in group of ratio 1∶1. GA contents in different groups were found lower than that of single Liquorice. Deposit produced from decorate solution after filtering were also analyzed. HPLC detection indicated that there only little GA and trace PE contained in deposit.

【关键词】 芍药甘草芍药甙甘草酸配伍
【Key words】 White Paeony rootLiquoricePaeoniflorinGlycyrrhizicCompatibility
  • 【文献出处】 时珍国医国药 ,LiShiZhen Medicine and Materia Medica Research , 编辑部邮箱 ,2000年02期
  • 【分类号】R284
  • 【被引频次】37
  • 【下载频次】527
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