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乳清蛋白水解配方奶粉治疗牛奶蛋白过敏性湿疹的临床研究

Clinical study on whey protein hydrolyzed formula in treatingpatients with allergic eczema caused by cow′s milk allergy

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【作者】 梁芙蓉李在玲蒋安惠杨艳玲赵凤临王丽德金子哲夫张京平卜学芳何德杨莉桑田有

【Author】 LIANG Furong,LI Zailing,JIANG Anhui, Pediatic Department,the First Teaching Hospital of Beijing Medical University,Beijing 100034,P.R.China

【机构】 北京医科大学第一医院儿科北京医科大学第三医院儿科北京医科大学康力天然保健品研究所日本明治乳业营养科学研究所日本

【摘要】 目的 观察乳清蛋白水解配方奶粉治疗牛奶蛋白过敏性湿疹的临床效果。方法 选择临床诊断为牛奶蛋白过敏性湿疹 37例 ,用乳清蛋白水解配方奶粉替代普通配方奶粉对患者进行膳食治疗 1~ 12个月 ,比较治疗前后过敏性湿疹及营养状态的变化。结果 治疗后 37例血嗜酸细胞计数 (EC)和皮肤特应性皮炎范围及严重度指数 (ADASI)均明显减少 (P<0 .0 0 1) ,相对体重 (RW)明显增加 (P <0 .0 0 5 )。其中 2 2例为特效 ,15例有效。 3例稀便 ,考虑为对此配方不耐受。结论 乳清蛋白水解配方奶粉治疗牛奶蛋白过敏性湿疹疗效显著

【Abstract】 Objective To observe the clinical effecttiveness of whey protein hydrolyzed formula(Nobiyaka) in the patients with eczema caused by cow′s milk allergy.Methods 37 patients with eczema caused by cow′s milk allergy were treated with Nobiyaka for 1 to 12 months instead of ordinary formula milk. The allergic symptoms and nutritional state were compared before and after treatment.Results After the treatment, blood eosinocytes and atopic dermatitis area and severity index(ADASI) decreased significantly in all patients (P<0.001). And relative weight increased significantly(P<0.005). Full effectiveness was recognized in 22 patients, and effectiveness in 15 patients;3 patients seemed to be intolerant to the formula, who showed dilute stool after the diet treatment.Conclusion Nobiyaka was noticeably effective for the patients with eczema secondary to cow′s milk protein allergy.

  • 【文献出处】 实用儿科临床杂志 ,JOURNAL OF APPLIED CLINICAL PEDIATRICS , 编辑部邮箱 ,2000年05期
  • 【分类号】R758.2
  • 【被引频次】14
  • 【下载频次】407
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