【摘要】 目的　用多普勒超声心动图探查冠状动脉内成形 +支架术 (PTCA+Stent)前后左室舒张功能的变化。方法　对 12例行 PTCA+Stent术的心绞痛患者 ,分别于术前 3～ 10 d(8± 3) d和术后 30～ 6 0 d(42±9) d,分别行多普勒超声心动图检查。并获得左室最大早期舒张血流速度 (E) ,晚期最大舒张血流速度 (A) ,得出舒张早期和晚期最大血流速度比 (E/A)和 E峰加速时间 (EAT) ,测出左房内径 (L A)。结果　 E峰、E/A术后较术前明显增大 (P均 <0 .0 0 1) ,A峰、EAT术后较术前明显减少 (P <0 .0 0 1,P<0 .0 5 ) ,L A术前后无差异 (P>0 .5 )。结论　 PTCA可使狭窄的冠状动脉通畅 ,心肌血流灌注正常或明显改善 ,显著改善冠心病患者的心肌缺血 ,使左室舒张功能改善更多还原

【Abstract】 Objective This study determines the changes in Doppler derived indexes of LV diastolic filling after percutaneous transluminal coronary angioplasty and stent implantation (PTCA+Stent) in patients with coronary heart disease.Methods PTCA+Stent were performed in 12 patients with angina pectoris.Doppler examination was done at baseline within 3～10 days (8±3) days before PTCA+Stent,and was repeated 30～60 days after PTCA+Stent,variables of LV diastolic function obtained in Doppler examination,including ①peak early diastolic flow velocity (E),②peak late diastolic flow velocity (A),③ratio of peak early and late diastolic flow velocities (E/A).④E spectral accelerated time (EAT),⑤left atrial diameter (LA).Results Peak E,E/A ratio increased significantly after PTCA+Stent.(0.54±0.81) vs (0.68±0.13) (P<0.001),(0.83±0.16) vs (1.19±0.23) (P<0.001),peak A,EAT showed a significant decrease after PTCA+Stent (0.68±0.15) m/s vs (0.58±0.08) m/s (P<0.001);(104±9) m/s vs (98.3±5.8) m/s (P<0.05).There was no significant difference in LA (29.7±2.9) mm vs (29.4±2.6) mm (P>0.5).Conclusion PTCA+Stent can revascularize in patients with coronary stenosis;myocardial blood flow perfusion can become normal or improve greatly,LV diastolic function be improved significantly.更多还原